Alternate methods of analysis using ADMIXTURE & PCAs

Alternate methods of analysis using ADMIXTURE & PCAs

The use of PCAs and ADMIXTURE program is widespread in the study of population histories, although the most common way those programs are used, using all available SNPs, including common variants, pruned for maximizing the genotype rate among samples in the dataset, may not be best for accurately inferring shared drift amongst populations. Here I outline some of the benefits of placing upper thresholds¬† on […]

Read Me 2 Comments

An Admixture Calculator for Eurasians

An Admixture Calculator for Eurasians

Genealogical testing companies use highly admixed references In other posts, I have mentioned the problems with ancestry proportion tests from genealogical testing companies such as 23andMe, AncestryDNA, and FTDNA, and how useless the test results can be for describing the population history and admixture for individuals from various parts of Eurasia. For example, what does it mean if you are say from Pakistan, and the […]

Read Me 11 Comments