Diploid Genotyping Low to Medium Coverage Ancient DNA – Part 1

Diploid Genotyping Low to Medium Coverage Ancient DNA – Part 1

OVERVIEW The overwhelming majority of published ancient DNA (aDNA) are pseudo-haploid genomes. This study focuses on the suitability and accuracy of these pseudo-haplodized aDNA genomes for various types of downstream analysis, such as those involving admixture allele frequency studies, as well as Identity-by-Decent (IBD) analyses and analyses using formal methods. The accuracy of pseudo-haploid aDNA genomes is also compared their diploid counterparts which were processed […]

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