A detailed look at East & North Eurasian Gene Flow to South & West Asians

A detailed look at East & North Eurasian Gene Flow to South & West Asians

Here I perform a detailed analysis of East and North Eurasian gene flow to South, South-Central, and West Asians by doing a one-to-one comparison of genomes sampled at about 404,000 Single Nucleotide Polymorphism (SNP) positions, using the program BEAGLE. To do this I utilize many genomes from northern and eastern Asia publicly available from the Estonian Biocentre. The results from my analysis are very surprising […]

Read Me 10 Comments

Characterising private and shared signatures of positive selection in 37 Asian populations

Characterising private and shared signatures of positive selection in 37 Asian populations

A new paper by Liu et al1 examines patterns of genetic diversity and positive natural selection, and finds that populations predominantly located in South Asia underwent considerably different adaptation as compared with populations from the other geographical regions. Here is their abstract: “The Asian Diversity Project (ADP) assembled 37 cosmopolitan and ethnic minority populations in Asia that have been densely genotyped across over half a […]

Read Me 4 Comments

23andMe’s New Admixture Date Estimator

23andMe’s New Admixture Date Estimator

I received a couple of inquiries asking what my thoughts were on the recently introduced 23andMe “Admixture Date Estimator”, which is detailed in their White Paper no. 23-14. Their theory appears mathematically and statistically sound, and appears to be heavily based on the size and distribution of the segments in your genome, however, the model assumes that admixture is inherited in a single pulse, which […]

Read Me 4 Comments

Elevated Eurasian Steppe Ancestry in Kurds

Elevated Eurasian Steppe Ancestry in Kurds

Here I investigate how much more genetic drift Kurds share with various ancient Eurasian Steppe samples, in comparison with some of their geographic neighbors. I do this formally using D-Statistics (Dstats) from ADMIXTOOLS1, a software bundle, readily available from the Reich Labs website at Harvard University. ADMIXTOOLS has been fully described in Patterson et al, 20122. The output of qpDstat is informative about the direction […]

Read Me 1 Comment